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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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C. Preventative Measures

Lifestyle changes can help prevent the spread of fungal infections of the vagina, liver, and brain (Ex. Alzheimer's medications). While using Cialis, focusing on easy exercise can help improve blood pressure, while daily alcohol intake might be limited. Limit alcohol consumption while using this medication.

Managed Care Centersare available to advice patients on how to take Cialis and recommend safe, effective measures to prevent infections. They can provide disease-specific advice and can provide guidance on prevention measures such as avoiding grapefruit juice, talking to your healthcare provider about your lifestyle, and avoiding alcohol while taking Cialis. Cialis is an prescriptions-only medication for erectile dysfunction, and is prescribed to men for up to 36 hours. It helps increase blood flow to the penis during sexual stimulation, facilitating an erection by increasing blood flow to the penis during sexual stimulation.

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Health authorities in several key countries have approved a drug called Tadalafil to treat erectile dysfunction. Unlike older medicines such as Viagra or Cialis, which can have side effects, tadalafil works by increasing blood flow to the penis, which helps men achieve and maintain an erection.

Tadalafil, which is sold under the brand name Cialis, is approved by the US Food and Drug Administration for treating ED.

According to the Mayo Clinic, tadalafil has also been approved for treating benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged.

How does tadalafil work?

Tadalafil works by increasing blood flow to the penis, which helps men achieve and maintain an erection. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors.

For men with ED, the drug relaxes the smooth muscle in the penis, allowing blood to flow into the penis when a man is sexually excited or aroused.

What are the side effects?

Like all medicines, tadalafil can cause side effects, although not everyone gets them.

The most common side effects of tadalafil are headache, flushing, nasal congestion, dizziness, and back pain.

If you experience any of these symptoms, seek medical attention immediately.

Is tadalafil safe?

Tadalafil is generally safe when used as directed, but it can cause side effects that last longer and can include:

  • Allergic reactions
  • Gastrointestinal issues
  • Heartworm disease
  • Low blood pressure
  • Diarrhea
  • Dizziness
  • Heartburn
  • Nausea

How do I take tadalafil?

For the best results, take tadalafil by mouth with 1-2 units of liquid as directed by your healthcare provider. Your provider may occasionally increase or decrease the dose.

Take tadalafil at about the same time each day as prescribed. Do not take it more often than 1 in 100 people; take it the same way every day.

Follow your provider’s instructions about how much tadalafil to take and how often to take it. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, take only that dose. Do not take two doses at a time.

What happens if I miss a dose?

If you have taken a dose too soon, you should not get an erection. If you have not taken a dose at all, you should not get an erection at all. However, if you take a dose quickly and without warning, avoid sexual activity for as long as possible to allow for sleep.

What can I do in case of an overdose?

If you suspect an overdose, contact a poison control center or emergency room immediately. Symptoms of a drug overdose may include:

  • Feeling better
  • Back pain

If you have not been seen by a health care professional in 10 days, seek medical attention immediately.

Symptoms of an overdose may include:

  • Flushing
  • Headache
  • Fatigue
  • Trouble sleeping

Can I drink alcohol while taking tadalafil?

It is not recommended to take tadalafil with alcohol while taking any of the following medications:

  • Nitroglycerin
  • Other alpha-blockers
  • Other cardiovascular medications
  • Other medications that can cause dilation of blood vessels.

It can be dangerous to drink alcohol while taking tadalafil.

Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

Read the "Patient Information Leaflet"for side effects or side effects not known on the day, orynew@h ().

Tadalafil may cause side effects with some respect to the bladder and the liver. Read the 'Tadalafil Side Effects' and 'Pregnancy & Breastfeeding Information leaflet' you refer to the patient information leaflet. side effects may differ from to to to. Some common side effects of tadalafil include:

  • Nausea/vomiting that won't go away.
  • Headache/dizziness.
  • Diarrhea.
  • Fatigue/ tired.
  • Insomnia.
  • Jaw/left edge reactions (such as flushing/hot flushes).
  • Burning or warmth in the face, tongue, or throat.
  • Stomach pain/ indigestion/ tiredness.
  • Upset stomach.
  • Vaginal itching or discharge.

If you are experiencing side effects in the past, you may want to look at potential side effects to consider starting new medication. The 'Side Effects and Precautions' page on our website provides information on potential side effects and side effects not available on the 'Patient Information Leaflets'.

For related medications, including 'Tadalafil for Erectile Dysfunction', our certified pharmacist will outlining the most common ones and any alternative treatments. You may also contact our pharmacy directly with any questions you may have.

Pharmacist alert: This medication may cause dizziness or affect your vision or hearing. Avoid the face/tongue/bladder sucker. The help of your doctor is needed. ED treatment is a medical emergency. We recommend that you discuss your medical history with your doctor.

Tadalafil may cause dizziness or affect your vision or hearing. Do not drive a car or operating machinery until you know how this medication affects you. Avoid the face/tongue sucker. BPH treatment: If you have problems with erection, you may need to take tadalafil generic for BPH medication treatment. Discuss all your other medical conditions with your doctor before taking tadalafil. The help of your doctor is also needed. Drug interactions may change how erect you are when you take tadalafil. You may want to avoid interaction with other medications you are taking. The 'Contraindications' page on our website provides information on possible contraindications and contraindications for tadalafil generic medication treatment.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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As with any prescription medication, there is potential for Cialis to cause serious side effects. These are not common or life-threatening, and may include:

  • Allergic reactions ( swelling of the lips, tongue, or throat)
  • Stomach pain
  • Pancreatitis
  • Severe dizziness
  • Trouble breathing

As with any prescription medication, there is possible side effects from Cialis. These may include:

  • Permanent changes in vision

As with all prescription medications, there is potential for side effects from Cialis.

  • Hives and swelling of the face, throat, tongue, and lips
  • Paresthesia
  • Decreased sex drive
  • Breast tenderness and enlargement